pentobarbital will lower the extent or result of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lessen the extent or effect of repaglinide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
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pentobarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral form of both equally agents. Small/Importance Unidentified.
Keep an eye on Closely (1)pentobarbital will reduce the level or influence of benzhydrocodone/acetaminophen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Caution when discontinuing CYP3A4 inducers which are coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may perhaps maximize and can result in likely deadly respiratory depression.
pentobarbital will lower the extent or effect of fludrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
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pentobarbital will decrease the level or impact of nateglinide by impacting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Watch.
pentobarbital will lower the level or result of fentanyl transdermal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of fentanyl with CYP3A4 get more info inducers may lead to your minimize in fentanyl plasma concentrations, lack of efficacy or, probably, improvement of a withdrawal syndrome inside of a affected individual who may have developed physical dependence to fentanyl.
pentobarbital will minimize the extent or result of darifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the extent or impact of itraconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.
Too fast administration may possibly cause respiratory melancholy, laryngospasm, apnea, or vasodilation with slide in hypertension
pentobarbital will lessen the extent or effect of tolbutamide by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Importance Not known.